ROCK2 and amyotrophic lateral sclerosis: A high MyBP-H expression level was also associated with the abnormal expression of Rho kinase 2 (ROCK2), LIM domain kinase 1 (LIMK1), and Cofilin2, indicating that the ROCK2/LIMK1/Cofilin2 pathway might play a role in ALS pathogenesis in muscles [220].