Such rearrangement of NF-κB2 has been reported in both B-cell and T-cell lymphoma patients suggesting that translocation dependent truncation of the ankyrin domain may be a common mechanism in the abnormal activation of NFKB2 gene and its relevant role in lymphomagenesis [15,148,153,155,156,157]. This evidence concerns the gene NFKB2 and T-cell non-Hodgkin lymphoma.