NF-κB signalling also contributes to tumour progression and invasion by controlling pro-angiogenic genes such as vascular endothelial growth factor (VEGF) and its receptors, macrophage inflammatory protein-1 (MCP-1) and CXC-chemokine ligand 8, also known as IL-8 (CXCL8) [203,204,205,206,207]. This evidence concerns the gene CCL2 and neoplasm.