RYR2 and Arrhythmogenic right ventricular dysplasia: In addition, mutations in the calcium-handling protein Ryanodine Receptor 2 (RYR2) [99], Phospholamban (PLN) [100], the adherens junction protein Cadherin 2 (CDH2) [101], Integrin-Linked Kinase (ILK) [102], the signaling molecule Transforming Growth Factor-β3 (TGFB3) [103], the cytoskeletal structure protein Titin (TTN) [104], Desmin (DES) [105], transmembrane protein 43 (TMEM43), and lamin A/C (LMNA) have also been reported in ARVC [24,106,107,108].