The authors, however, noted that this occurred in a type I IFN-independent manner as there were no differences in disseminated intravascular coagulation (DIC) markers, including fibrinogen, D-dimer, fibrin, and TF release in the plasma of Ifnar−/− mice compared with wild-type mice 48 h after CLP-induced sepsis. The gene discussed is IFNAR1; the disease is Sepsis.