TM4SF19 and head and neck squamous cell carcinoma: On the other hand, the lncRNA TM4SF19-AS1 acts as a sponge for miR-153-3p since it binds to LAMC1 (laminin gamma 1 subunit), which has been reported to be upregulated in patients with HNSCC [37]; thus, TM4SF19-AS1 enhances proliferation, migration, invasion, and epithelial–mesenchymal transition (EMT) through the expression of mesenchymal markers (vimentin, N-cadherin) [38].