Thirty-five of 86 (40%) of the PLWH and 10 of 32 (31%) of the non-HIV-infected individuals carried mutations with VAF between 0.5 and 1%, which may explain the identification of mutations less commonly associated with CH in this study, such as somatic TP53 and ARID1A, which were only found in the PLWH [23]. This evidence concerns the gene TP53 and cyclic hematopoiesis.