HLA-B and toxic epidermal necrolysis: The allele HLA-B*57:01 is unambiguously associated with SJS/TEN following treatment with CBZ in Europeans [24]: The analysis included 28 European patients with CBZ-induced SJS, SJS/TEN-overlap or TEN, 11 of them were carrying HLA-B*57:01 (39.29%), whereas the frequency of this allele was 6.69% in European general population controls.