When compared with other p-tau species, CSF p-tau235 performance discriminating dementia Aβ+ from dementia Aβ− was equal to CSF p-tau181 (AUCDementiaAβ− vs Aβ+=0.92, CI95%=0.84–0.97) and CSF p-tau231 (AUCDementiaAβ− vs Aβ+=0.88, CI95%=0.79–0.94). The gene discussed is MAPT; the disease is dementia.