Advances in next‐generation sequencing and genome‐wide association analyses have unraveled significant heterogeneity in medulloblastoma [12], such that the World Health Organization Classification of Tumors of the Nervous System has for some time classified MBs into molecular subgroups: wingless (WNT)-activated, sonic hedgehog (SHH)-activated and TP53 wildtype, SHH-activated and TP53 mutant, and non-WNT/non-SHH [24]. The gene discussed is TP53; the disease is Mobius syndrome.