We detected Timm13 in fibrotic liver tissues and hepatocytes at the mRNA level, and our results indicated significant downregulation of Timm13 mRNA in liver fibrosis models and cell models (F4W, P = 0.0414; F6W, P = 0.0365; 5 ng/mL, P = 0.0119; 10 ng/mL, P = 0.0078; 20 ng/mL, P = 0.024) (Fig. 6; *P < 0.05, **P < 0.01). The gene discussed is TIMM13; the disease is Hepatic fibrosis.