Regardless of HF subtype, patients initiating DPP4i (compared to SGLT2i) were older and more likely to be diagnosed with MI, peripheral vascular disease and renal insufficiency, while those initiating GLP-1RA (compared to SGLT2i) were more likely to be female, have previously used insulin, and have evidence of microvascular complications of diabetes. Here, INS is linked to Renal insufficiency.