To examine in ovarian cancer OVCAR-5 cells the ability of L. indica extract-mediated induction of activating ligands for NK cell receptors (DNAM-1 and NKG2D), the cancer cells were treated with the ethyl acetate fraction, and subsequently analyzed for the stress ligands by immunofluorescence conjugated specific monoclonal antibodies. This evidence concerns the gene KLRD1 and ovarian cancer.