AGR2 and Cirrhosis: Multivariate analysis showed that cirrhosis (P = 0.034, HR = 4.563, CI = 1.122–18.555), BCLC stage (P < 0.001, HR = 2.928, CI = 1.908–4.494), and a high AGR2 level (P = 0.008, HR = 1.735, CI = 1.154–2.609) were independently associated with OS (Table 3).