AGR2 and Cirrhosis: Multivariate analysis showed that cirrhosis (P = 0.023, HR = 1.600, CI = 1.067–2.401), vascular invasion (P = 0.005, HR = 1.825, CI = 1.198–2.780), and a high AGR2 level (P = 0.043, HR = 1.662, CI = 1.017–2.716) were independently associated with RFS (Table 5).