While diabetic retinopathy can be vision-threatening, proper management of diabetes and ophthalmic interventions like pan-retinal photocoagulation (PRP) and intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents have shown to be effective and have become the current standard of care in managing diabetic retinopathy at various stages of its progression [20]. The gene discussed is VEGFA; the disease is diabetic retinopathy.