For example, CRP-to-albumin score, the Glasgow Prognostic Score (GPS) each have an independent prognostic value in patients with PC [14]. A high neutrophil-to-lymphocyte ratio (NLR) is associated with an adverse overall survival (OS) in pancreatic cancer [15]. A low fibrinogen-to-albumin ratio (FAR) was positively correlated with a good OS in locally advanced or metastatic PC [16]. The gene discussed is ALB; the disease is pachyonychia congenita.