This effect was confirmed in many subsequent reports (Gumá et al. 2004; Heatley et al. 2013; Hendricks et al. 2014; López-Botet et al. 2014; Lopez-Vergès et al. 2011; Muntasell et al. 2013), highlighting the critical role of NKG2C in HCMV infection, but from the other side uncovered the impact of HCMV on NK cell subsets composition. Here, KLRC2 is linked to cytomegalovirus infection.