ALDH3B1 and lung cancer: The sub-group analysis stratified by pack-years revealed a significant association of rs3764821 of ALDH3B1 in both low pack-years (< 47 py) (OR = 2.58, 95% CI = 1.13–5.88, p = 0.024*) and high pack-years (≥ 47 mean py) (OR = 2.73, 95% CI = 1.49–5.01, p = 0.0012**) subgroups with risk of lung cancer in the additive model.