However, in an attempt to independently replicate the three rSNVs rs3764821 (ALDH3B1), rs3748523 (RAD52), and rs5742926 (PMS1) from our case–control association study, we failed to find any significant association of the variants with lung cancer in the white British population, which differs from our finding in the east Indian population. The gene discussed is PMS1; the disease is lung cancer.