Globally, plasma NfL levels were found to be higher in patients with a dementia (AD and FTD together) (MED: 26.95 IQR: 19.45 pg/mL) when compared with the HC (MED: 8.31 IQR: 4.67 pg/mL; p < 0.0001; AUC = 0.95). This evidence concerns the gene NEFL and dementia.