CCN4 and acute respiratory distress syndrome: TNF‐α, IL‐6 (Wang et al., 2015), IL‐1β, TGF‐β1 (Ganter et al., 2008), CINC‐1 (Sawant et al., 2015), TIMP1 (Madtes et al., 2001), and WISP‐1 protein (Li et al., 2012) have been reported to contribute to the development of ALI.