The pooled rate of grade 3 to 4 AEs was 26.9% (95% CI: 7.8%–45.9), and the common AEs to triple therapy included leukopenia (25%), thrombocytopenia (23.8%), fatigue (23.2%), gastrointestinal discomfort (22%), increased alanine aminotransferase (22%), and neutropenia (21.4%). The gene discussed is GPT; the disease is Decreased total leukocyte count.