TINCR and diabetic cardiomyopathy: Meanwhile, previous research demonstrated that METTL14-mediated m6A methylation modification suppressed pyroptosis and diabetic cardiomyopathy by down-regulating TINCR.[18] Interestingly, the m6A methylation of XIST was prominently reduced, but the level of XIST was obviously over expression.[19] Notwithstanding, no studies have authenticated the absolute regulatory relationship between m6A methylation levels and lncRNA expression, which requires further in-depth research.