LRRC32 and inborn error of immunity: Indeed, a growing number of studies support a key role for GARP in immune regulation, with knockdown or inhibition of GARP reducing Treg-mediated suppression of T-effector cell activity and rare coding mutations in LRRC32 being associated with primary immunodeficiency and atopic dermatitis (Cuende et al., 2015; Lehmkuhl et al., 2021; Manz et al., 2016; Wang et al., 2010).