RAB10 and Alzheimer disease: In this light, promoting the delivery of Rab10 organelles to nerve terminals may be explored as an novel therapeutic strategy for diseases in which the endolysosomal system is overloaded or dysfunctional, such as Alzheimer’s disease (Van Acker et al., 2019; Xu et al., 2018), or to increase the ability of axons to respond to trophic factors during regeneration.