MMR gene-related cancers, including pancreatic cancer, are associated with MSI and MMR gene dysfunction, and the presence of MMR gene dysfunction or MSI-high is a known LS predictor and increases cancer risk (Laghi et al., 2012; Hause et al., 2016; Nojadeh et al., 2018). The gene discussed is MRC1; the disease is pancreatic neoplasm.