Among these genes, Breast Cancer 1 (BRCA1) and Breast Cancer 2 (BRCA2) have been reported to have variations that increase the risk of developing breast and ovarian cancers by more than 60% basically suggesting these variations as one of the leading causes of breast and ovarian cancers (Gradishar et al., 2022). The gene discussed is BRCA1; the disease is breast carcinoma.