The results from GEPIA2 database showed that ADIPOR1 was upregulated in BRCA, CESC, CHOL, COAD, glioblastoma multiforme (GBM), brain lower grade glioma (LGG), LIHC, ovarian serous cystadenocarcinoma (OV), PAAD, PCPG, PRAD, READ, and STAD, but was downregulated in lymphoid neoplasm diffuse large B-cell lymphoma (DLBC), acute myeloid leukemia (LAML), and thymoma (THYM); ADIPOR2 was upregulated in DLBC, KICH, LGG, PAAD, skin cutaneous melanoma (SKCM), testicular germ cell tumors (TGCT), and THYM, but was downregulated in LUAD, OV, PCPG, THCA, UCEC, and uterine carcinosarcoma (UCS) (Figure 2C). The gene discussed is ADIPOR2; the disease is cutaneous melanoma.