NPPB and heart failure: An E/e’ >15 is consistent with an elevated LVEDP that should prompt diuresis 50, 51.Studies have shown an E/e’ >15 in the point of care setting to be 100% sensitive and 95% specific for heart failure when found in conjunction with B lines on lung ultrasound, also performing better than other modalities such as BNP and chest x-ray for diagnosing decompensated heart failure 50.