ST6GALNAC5 and cancer: Research conducted by Chang G et al. shows that YTHDF3 promotes cancer cell interactions with brain endothelial cells and astrocytes, BBB extravasation and angiogenesis via enhancing the translation of m6A-enriched transcripts for ST6GALNAC5, GJA1 and epidermal growth factor receptor (EGFR), which are all associated with cancer brain metastasis (Chang et al., 2020).