NPPB and congenital rubella syndrome: In the Shalabi et al. (23) cohort, 13 patients underwent troponin levels dosage during CRS: 4 cases resulted with abnormal troponin values, all of them associated with cardiac dysfunction quantified by decreased LVEF; NTpro-BNP was assessed only in 7 patients and proved to be elevated during CRS, with the highest values observed in two patients with cardiac impairment developed during CRS (23).