IL6 and hypertensive disorder: Zhang et al. showed that the administration of ferrostatin-1 (Fer-1; ferroptosis inhibitor) significantly prevented pathological myocardial remodeling, dysfunction, and ultrastructural injury in mice with hypertension by suppressing interleukin-6 (IL6)/STAT3 signaling and activating the xCT/glutathione peroxidase (GPX4) signaling (9).