A logistic regression analysis including (as independent variables) sclerostin, total cholesterol, triglycerides (classified as dichotomic variables according to medians), CKF, cirrhosis, diabetes, and hypertension showed that sclerostin was the only variable independently related to the presence of vascular calcifications (p = 0.022; odds ratio for calcifications if sclerostin is over the median = 2.65 (95% CI = 1.14–6.13). The gene discussed is SOST; the disease is Hypertension.