SPP1 and colorectal carcinoma: Univariate Cox regression analysis showed that mRNA levels of SPP1 more than cut-off were associated with decreased rates of DFS (HR=2,22; 95% CI [1,382-3,595], p=0,001) and PFS (HR=2,20; 95% CI [1,382-3,526], p=0,0009) in the CRC group (Supplementary Table S11).