S100A4 and neoplasm: Multivariate Cox analysis displayed that S100A4 mRNA expression more than 11,68 (HR=9,97; 95% CI [5,800-17,150], p<0,0001), large tumor size (HR=2,41; 95% CI [1,216-4,790], p=0,011) and positive vascular invasion (HR=2,36; 95% CI [1,357-4,097], p=0,002) were associated with worse PFS in CRC patients (Supplementary Table S5).