S100A4 and rectal cancer: Using GSE190826 cohort we showed that pre-treatment S100A4 mRNA expression in rectal cancer patients who had not achieve pathological complete response (pCR) after CRT and suffered from the recurrence, was lower than in patients without progression (7,25 ± 0,81 vs. 6,64 ± 0,82, p=0,049) (Figure 6B).