We found that five cuprotosis molecules, DLAT, PDHA1, FDX1, GLS and CDKN2A, were significantly different between paired tumour and adjacent non-tumour samples from the TCGA-STAD cohort (Fig. S2A), and LIAS, DLD, DLAT and MTF1 were significantly different among the four pathologic T categories 1–4 (Fig. S2B). Here, CDKN2A is linked to neoplasm.