On the contrary, some studies reject increased interictal levels of IL-6, IL-1B, and IL-1Ra in epilepsy patients, and report only postictal increase (within 24 h after a seizure/ictal event) in IL-6 after TLE, XTLE, and focal epilepsy, or postictal increase in IL-6 in TLE and not in XTLE patients [12,[14], [15], [16], [17], [18]]. Here, IL6 is linked to epilepsy.