ICAM1 and influenza: Nevertheless, following influenza infection, the homing of OT-I CD8+ T cells into ICAM-1/2-/- MedLNs was only partially reduced (Figure 6C; 3rdvs. 4th column), and the residual CD8+ OT-I T cell homing observed could be completely blocked by anti α4 integrin mAb treatment (Figure 6C; 4thvs. 5th column).