Further in vitro experiments also found that Z8 has a low EC50 and can inhibit the malignant biological behaviors of KK-LC-1 high expressed triple-negative breast cancer cells MDA-MB-231 and MDA-MB-468 by MAL2/MUC1-C/PI3K/AKT/mTOR pathway. Here, MAL2 is linked to triple-negative breast carcinoma.