SH-NKG2D-CAR-NK92 cells produced remarkable antitumor ability compared with NK92 cells and NC-NKG2D-CAR-NK92 cells in vivo, the tumor volume and weight were lower in the group treated with SH-NKG2D-CAR-NK92 cells than that with NC-NKG2D-CAR-NK92 cells (Fig. 6A–C). The gene discussed is KLRK1; the disease is neoplasm.