S100A7A and alkaline phosphatase measurement: Among the 55 highly expressed proteins (P < 0.10 by Mann–Whitney U test) in the AP group, negative correlation was shown by 4 proteins, viz., protein S100-A7A (Uniprot ID, Q86SG5), eukaryotic translation initiation factor 1 (P41567), serpin B4 (P48594), and peptidoglycan recognition protein 1 (O75594) (P < 0.10 by Spearman’s test; Table 2 and Fig. 2).