ACE2 and viral infectious disease: Notably, a number of additional genes localized to SMARCA4-dependent genomic regions were those found to mediate viral infection in our CRISPR screen along with ACE2, such as SLC4A4 and HNF1A (Fig. 2e and Extended Data Fig. 4f), thus suggesting that mSWI/SNF complexes regulate a coronavirus susceptibility gene expression axis.