MAPT and Alzheimer disease: The evolution of seeding competent protein species from liquid-condensed protein phases was suggested to play a role for the pathological activity and aggregation of FUS, hnRNPA1, and TDP-43 in amyotrophic lateral sclerosis17,18, for alpha-synuclein in Parkinson’s disease19, and for Tau in AD and FTD20,21.