PVT1 and MIR205HG expression levels were examined in 20 patients with lymph node-negative HNSCC (LN negative group) compared with that in 20 patients with lymph node-positive HNSCC (LN positive group) who were matched for treatment modality, TNM stage, pathological differentiation, location of the primary carcinoma, sex, and age. The gene discussed is PVT1; the disease is medical procedure.