Compared to the control groups, the protein abundance of REV-ERBα was decreased in the healthy area (Control: 21.294% vs. healthy area from IPF: 11.296%) from IPF samples, and slightly increased protein levels of COL1A1 (Control: 37.074% vs. healthy area from IPF: 52.604%) and LOX (Control: 30.439% vs. healthy area from IPF: 40.836%) in the healthy areas from IPF samples compared to control group were observed (Fig. 1). The gene discussed is NR1D1; the disease is idiopathic pulmonary fibrosis.