Epithelial-mesenchymal transition (EMT) is a key stage in the process of CRC metastasis [13], which is applied to detect whether LOC105369504 suppressed metastasis mediated by EMT.E-cadherin was employed as the epithelial marker of CRC cells and vimentin and N-cadherin served as mesenchymal markers in western blots. The gene discussed is CDH2; the disease is colorectal carcinoma.