KAT8 and diffuse large B-cell lymphoma: This physical interaction was readily detected in native GC-derived cells exemplified by the two GCB-DLBCL cell lines SUDHL4 and LY7 that carry wild-type KMT2D alleles and intact lysine acetyltransferase genes (KAT1-KAT8 families) (Fig. 4 B and C).