We compared the proportional hazard ratios for DFS and OS in patients receiving only surgery with those also receiving PST, using a forward stepwise approach with 6 factors, as follows: size of invasive tumor, number of metastatic lymph nodes, and the degree of infiltration of CD8+ , PD-L1+ , FOXP3+ or CD68+ immune cells at primary site as a percentage of absolute values. The gene discussed is CD68; the disease is neoplasm.