NPPB and heart failure: Unfortunately, the earliest stage of heart failure in which NT‐pro/BNP values may be elevated is stage B.1, 14, 15In a study evaluating the prognostic value of NT‐proBNP for death and cardiovascular events in both healthy subjects and subjects with stage A/B heart failure, the authors found that NT‐proBNP was not predictive of morbidity or mortality in healthy subjects.16