IFNL1 and neoplasm: Strikingly, blocking Fuc residues on tumor cells (using soluble UEA-I) incredibly enhanced production of cytokines by DCs compared to co-culture with untreated tumor cells (up to 53.7% of IFNλ1+ cDC1s compared to 31.53%; up to 26.03% of IFNα+ pDCs compared to 11.69%) (Figure 5C).