Resatorvid (TAK-242) is a newly developed, highly selective Toll-like receptor 4 (TLR4) antagonist that is effective for treating pulmonary inflammation (Wang et al., 2016), rheumatoid arthritis (Samarpita et al., 2020), and acute kidney damage (Mohammad et al., 2018). The gene discussed is TLR4; the disease is rheumatoid arthritis.