NLRP3 and cancer: The expression of ATP7A, SLC31A1, LIAS, LIPT1, LIPT2, DLD, DLAT, PDHA1, PDHB, MTF1, GLS, CDKN2A, and DLST was upregulated, while NLRP3 and DBT were downregulated in cancer tissues than in the normal tissues (Figure 5A).