These miRNAs include miR-199a-5p (upregulated in DMD muscle cells and downregulated in DMD fibroblasts (Zanotti et al., 2018)), involved in the wingless-related integration site (WNT) signaling pathway (targeting numerous myogenic cell proliferation and differentiation regulatory factors) (Alexander et al., 2013), and miR-29, a targeter of AKT Serine/Threonine Kinase 3 (AKT3)/nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB)/Yin Yang1 (YY1) signaling and fibrotic genes (Wang et al., 2012). The gene discussed is AKT1; the disease is Duchenne muscular dystrophy.